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Table 1 Baseline characteristics of included studies

From: Association of soft drinks and 100% fruit juice consumption with risk of cancer: a systematic review and dose–response meta-analysis of prospective cohort studies

Author, Year

Name of cohort

Country

Sample size

Duration of follow-up (year)

Age, year

Female, %

Types of exposure

Types of outcomes

MICHAUD [31]

The Health Professionals Follow-up Study

USA

47,909

10

NR

0

Fruit juice

Bladder cancer

Ellison [32]

NCS

Canada

3400

NR

50 to 84 years

0

SSB

Prostate cancer

Schernhammer [16]

NHS

USA

88,794

20

46.30

100

SSB; ASB

Pancreatic cancer

Schernhammer [16]

HPFS

USA

49,364

20

47.73

0

SSB; ASB

Pancreatic cancer

Larsson [33]

SMC

USA

35,273

7.2

62.08

100

SSB

Pancreatic cancer

Larsson [33]

COSM

USA

42,524

7.2

59.7

0

SSB

Pancreatic cancer

Lee [34]

NHS

USA

68,738

20

52.98

100

SSB

Kidney cancer

Lee [34]

HPFS

USA

47,918

14

54.43

0

SSB

Kidney cancer

Nöthlings [35]

Multiethnic Cohort Study

USA

162,150

8

59.76

55.1

Fruit juice

Pancreatic cancer

Bao [36]

NIH-AARP Diet and Health Study

USA

487,922

7.2

62.17

0

SSB; ASB; Total soft drinks

Pancreatic cancer

Ren [37]

NIH-AARP Diet and Health Study

USA

481,563

NR

50–71

40.53

SSB

Oral; pharynx; larynx; esophagus; gastric cancer

Mueller [38]

SCHS:

Singapore

60,524

14

56.33

55.9

SSB; Fruit juice

Pancreatic cancer

Fung [39]

NHS + HPFS

USA

132,392

26

NR

100

SSB

Colorectal cancer

Zhang [40]

Pooled analysis

China

731,441

6–20

25–90

NR

SSB

Colon cancer

Ros [41]

EPIC

Europe

233,236

9.3

25–70

NR

Total soft drink

Urinary tract cancer

Allen [42]

Million Women Study

UK

779,369

5.2

59.4

100

SSB; Fruit juice

Kidney cancer

Friberg [43]

SMC

Sweden

61,226

18.4

53.83

NR

Total soft drink

Endometrial cancer

Drake [44]

MDC

Sweden

28,098

14.9

59.00

60.63

SSB; Fruit juice

Prostate cancer

Schernhammer, 2012 [18]

NHS

USA

77,218

22

53.70

100

SSB; ASB

Non-Hodgkin lymphoma; Myeloma; Leukemia

Schernhammer, 2012 [18]

HPFS

USA

47,810

22

50.60

0

SSB; ASB

Non-Hodgkin lymphoma; Myeloma; Leukemia

Inoue-Choi 2013 [45]

IWHS

USA

41,836

4

61.62

100

SSB; 100% Fruit juice

Endometrial Cancer

Stepien [46]

the European Prospective Investigation into Cancer and Nutrition cohort

Europe

477,206

11.4

51.21

70.2

Total soft drinks

Liver cancer

Odegaard [47]

SCHS

China

52,584

16.3

55.77

56.02

SSB; 100% Fruit juice

Overall cancer

McCullough [48]

CPS-II Nutrition Cohort

USA

100,442

10

69.20

56.84

SSB; ASB

Non-Hodgkin lymphoma

Wu [49]

HPFS

USA

41,530

24–26

53.31

0

Fruit juice

Basal cell carcinoma; squamous cell carcinoma

Wu [49]

NHS

USA

63,759

50.09

100

Fruit juice

Basal cell carcinoma; squamous cell carcinoma

Wu [50]

HPFS

USA

105,432

NR

NR

NR

Fruit juice

Melanoma

Hodge [51]

MCCS

Australia

35,393

11.6

54.69

60.38

SSB; ASB

Overall; Prostate; Ovary; Kidney; Colorectal; Breast; endometrial; Gastric cancer

Zamora-Ros [52]

EPIC

Europe

519,978

14

35–70

70

Fruit juice

Thyroid cancer

Miles [53]

PLCO

Canada

38,343

9

65.6

0

SSB; ASB; Fruit juice

Prostate Cancer

Makarem [54]

FOS

USA

3418

NR

54.34

52.98

SSB; Fruit juice

Breast; Prostate; Colorectal cancer

Bassett et al. [55]

MCCS

Australia/New Zealand/other, United Kingdom; Italy; Greece

35,109

19

54.7

60.69

SSB

Prostate; lymphoma; gastric; Melanoma; breast; bladder; Brain cancers; Leukemia

Luo et al. [56]

NHS

USA

87943

32

58.65

100

SSB

Liver cancer

Luo et al. [56]

HPFS

USA

49665

  

0

SSB

Liver cancer

Pacheco et al. [57]

CTS

USA

99798

20

51.58

100

SSB

Colorectal Cancer

Romanos-Nanclares [58]

SUN

Spain

10713

10

34.76

100

SSB

Breast cancer

Chazelas,2019 [13]

NutriNet-Santé prospective cohort

French

101257

5.1

42.2

78.7

SSB; ASB; Fruit juice

Overall; Breast; Colorectal; Prostate cancer

Debras [59]

NutriNet-Santé cohort

France

101,279

5.9

40.8

78.73

SSB

Breast cancer

 

Hokkaido

Japan

3158

14.3

58.00

51.74

SSB

Overall, colorectal cancer

Heath [60]

EPIC

Europe

389,220

15

68.00

51.80

Total soft drink; SSB; ASB; Fruit juice

Kidney cancer

Arthur [61]

CSDLH

Canada

73,909

12

NR

53.60

SSB; Fruit juice

Breast, Endometrial, Ovarian, Colorectal cancer

Hur [62]

NHSII

USA

95,464

24

41.55

100

SSB; ASB, Fruit juice

Colorectal cancer

Chen [63]

HMAC

China

491,929

25

39.9

52.14

SSB

Pancreatic cancer

Romanos-Nanclares [64]

NHSII

NHS

USA

90,085

82,713

26

36

36.5

46.2

100

SSB; ASB;

Breast cancer

Yuan [65]

HPFS

NHS

USA

51,529

121,700

28

30

40–75

30–55

0

100

SSB

Overall, Colon, Rectum cancer

Ringel [66]

NR

USA

93,676

13.5

50–79

100

ASB

Urinary tract cancer

  1. EPIC European Prospective Investigation into Cancer and Nutrition, NHS Nurses’ Health Study, SCHS Singapore Chinese Health Study, CPS Cancer Prevention Study, IWHS Iowa Women’s Health Study, MDC Malmo¨ Diet and Cancer, SMC Swedish Mammography Cohort, COSM Cohort of Swedish Men, MCCS Melbourne Collaborative Cohort Study, CTS California Teachers Study, PLCO Prostate, Lung, Colorectal, and Ovarian, NCS Nutrition Canada Survey, FOS The Framingham Offspring, SUN Seguimiento Universidad de Navarra, HMSC Half a Million Asian Cohort, SSB sugar sweetened beverages, ASB artificially sweetened beverages