Accelerometry-assessed physical activity and sedentary time and associations with chronic disease and hospital visits - a prospective cohort study with 15 years follow-up

Table 3 Associations between physical activity and sedentary time and combined morbidity, i.e. registered hospital visits due to any of the included diagnoses (cardiovascular disease, cancer, type 2-diabetes, dementia, obesity or depression), for participants without reported heart disease, cancer or diabetes at baseline

Combined morbidity	Model 1		Model 2		Model 3
n = 1132 / 286 events	HR	95% CI	HR	95% CI	HR	95% CI
Sedentary time
Tertile 1	1		1		1
Tertile 2	1.33	1.00, 1.76	1.07	0.81, 1.42	1.07	0.80, 1.42
Tertile 3	1.24	0.91, 1.68	1.19	0.88, 1.62	1.18	0.87, 1.61
Light-intensity PA
Tertile 1	1		1		1
Tertile 2	1.11	0.83, 1.47	1.07	0.80, 1.42	1.08	0.81, 1.43
Tertile 3	0.89	0.67, 1.19	0.90	0.67, 1.20	0.90	0.67, 1.21
Moderate-to-vigorous PA
Tertile 1	1		1		1
Tertile 2	0.64	0.49, 0.84	0.90	0.68, 1.19	0.90	0.68, 1.20
Tertile 3	0.44	0.32, 0.59	0.64	0.48, 0.87	0.65	0.48, 0.88
Total activity counts
Tertile 1	1		1		1
Tertile 2	0.90	0.68, 1.20	0.94	0.71, 1.25	0.94	0.71, 1.25
Tertile 3	0.54	0.41, 0.73	0.64	0.48, 0.86	0.64	0.48, 0.86

Cox proportional-hazard models were used to estimate hazard ratios (HR) with 95% confidence intervals (CI). Model 1: crude. Model 2: adjusted for age, sex, smoking (missing = 5), and education (missing = 4). Model 3: adjusted for model 2 variables plus hypertension and arthritis (missing = 13) at baseline. All models for sedentary time additionally adjusted for wear time. Statistically significant results shown in bold
PA physical activity

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