Table 1 Characteristics of 1078 men without pre-existing diabetes, CVD or heart failure, % (n) or mean (SE)

N ^a

287^a

275^a

268^a

248^a

1078

Age (years), mean (SE)

77.3 (0.2)

77.8 (0.3)

79.1 (0.3)

79.9 (0.3)

<0.0001

1078

0

Non-manual social class, % (n)

53.9 (154)

59.5 (163)

53.2 (141)

50.0 (123)

0.18^b

1071

7

Living alone, % (n)

14.6 (41)

15.1 (41)

19.9 (53)

24.4 (60)

0.01^b

1064

14

Smoking, % (n)

1.8 (5)

1.1 (3)

4.6 (12)

7.0 (17)

0.001^c

1062

16

Alcohol (units per week), mean (SE)

6.9 (0.5)

6.7 (0.5)

6.3 (0.5)

5.7 (0.4)

0.06

1047

31

% day spent in SB, mean (SE)

61.5 (0.4)

70.5 (0.3)

75.3 (0.3)

80.7 (0.4)

<0.0001

1078

0

SB (mins/day), mean (SE)^d

509 (3)

591 (1)

644 (1)

720 (2)

<0.0001

1078

0

LPA (mins/day), mean (SE)^d

256 (2)

209 (1)

184 (1)

153 (2)

<0.0001

1078

0

MVPA (mins/day), mean (SE)^d

66.8 (1.9)

42.4 (1.4)

31.6 (1.1)

22.0 (1.0)

<0.0001

1078

0

BMI (kg/m²), mean (SE)^d

26.3 (0.2)

26.7 (0.2)

26.9 (0.2)

27.3 (0.3)

<0.0001

1068

10

WC (cm), mean (SE)^d

97.0 (0.5)

98.4 (0.60)

99.8 (0.6)

100.3 (0.8)

<0.0001

1072

6

FMI (kg/m²), mean (SE)^d

9.8 (0.2)

10.1 (0.2)

10.5 (0.2)

10.7 (0.2)

<0.0001

1009

69

Insulin (mmol/l), mean (SE)^d

7.8 (0.3)

9.3 (0.4)

9.6 (0.4)

8.5 (0.3)

<0.0001

1010

68

MS, % (n)

18.5 (48)

20.6 (51)

24.2 (56)

25.5 (55)

0.23

954

124

1

2

3

4

(0.4 – <3.1)

(≥3.1 – <30.8)

(≥30.8 – <53.5)

(≥53.5)

P (trend)

N

N missing

N ^a

226^a

270^a

286^a

296^a

1078

Age (years), mean (SE)

8.4 (0.3)

78.6 (0.3)

78.1 (0.2)

76.6 (0.2)

<0.0001

1078

0

Non-manual social class, % (n)

48 (109)

55 (148)

55 (158)

57 (166)

0.25^b

1071

7

Living alone, % (n)

21 (47)

19 (52)

19 (53)

15 (43)

0.28^b

1064

14

Smoking, yes % (n)

6.3 (14)

4.5 (12)

1.4 (4)

2.4 (7)

0.013^c

1062

16

Alcohol (units per week), mean (SE)

5.2 (0.5)

6.1 (0.5)

6.9 (0.5)

7.2 (0.5)

0.001

1047

31

% time spent Sedentary, mean (SE)

81.3 (0.4)

75.0 (0.3)

70.1 (0.3)

62.7 (0.4)

<0.0001

1078

0

SB(mins/day), mean (SE)^d

672 (4)

636 (3)

605 (3)

551 (4)

<0.0001

1078

0

LPA (mins/day), mean (SE)^d

148 (3)

190 (3)

216 (3)

242 (3)

<0.0001

1078

0

MVPA (mins/day), mean (SE)^d

7.2 (0.2)

22.2 (0.3)

41.5 (0.4)

85.3 (1.6)

<0.0001

1078

0

BMI (kg/m²), mean (SE)^d

27.5 (0.3)

27.3 (0.2)

26.5 (0.2)

26.0 (0.2)

<0.0001

1068

10

WC (cm), mean (SE)^d

101.3 (0.8)

100.5 (0.6)

98.1 (0.6)

96.0 (0.5)

<0.0001

1072

6

FMI, (kg/m²), mean (SE)^d

10.9 (0.2)

10.7 (0.2)

10.1 (0.2)

9.6 (0.2)

<0.0001

1009

69

Insulin (mmol/l), mean (SE)^d

9.4 (0.5)

9.9 (0.4)

8.5 (0.3)

7.7 (0.3)

<0.0001

1010

68

MS, % (n)

27.1 (52)

28.7 (68)

20.6 (52)

14.0 (38)

<0.0001

954

124