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Table 2 Cardio-metabolic changes from baseline to 12 months for participants completing a 12 month weight-loss trial 1

From: Patient freedom to choose a weight loss diet in the treatment of overweight and obesity: a randomized dietary intervention in type 2 diabetes and pre-diabetes

Variable

Diet group

 

All (n = 96)

No Choice (n = 49)

Choice (n = 47)

 

Baseline change

Baseline change

Baseline change

SBP (mmHg)

140.8 ± 18.1

-6.4 ± 17.4§

142.9 ± 19.5

-6.7 ± 17.5

138.5 ± 16.6

- 6.2 ± 17.4

DBP (mmHg)

84 ± 10.8

-3.9 ± 10.8§

85.0 ± 11.4

-5.0 ± 10.1

82.7 ± 10.2

-2.7 ± 11.6

HbA1c (%)

7.02 ± 1.26

-0.15 ± 0.79

7.04 ± 1.28

-0.19 ± 0.82

6.99 ± 1.26

-0.11 ± 0.77

Fasting Glucose (mmol/L)

7.47 ± 2.28

-0.42 ± 1.75§

7.51 ± 2.50

-0.53 ± 1.94

7.41 ± 1.93

-0.31 ± 1.53

Triglycerides (mmol/L)

1.79 ± 0.89

-0.09 ± 0.89

1.85 ± 0.97

-0.26 ± 0.76

1.73 ± 0.79

0.09 ± 0.98

Total cholesterol (mmol/L)

4.50 ± 1.13

-0.01 ± 0.61

4.33 ± 0.94

-0.05 ± 0.60

4.67 ± 1.29

0.03 ± 0.63

HDL cholesterol (mmol/L)

1.20 ± 0.45

-0.05 ± 0.35

1.13 ± 0.24

-0.01 ± 0.16

1.28 ± 0.59

-0.09 ± 0.47

LDL cholesterol (mmol/L)

2.46 ± 1.01

0.12 ± 0.61

2.26 ± 0.89

0.15 ± 0.68

2.66 ± 1.10

0.08 ± 0.52

hs-CRP (mg/L)

2.96 ± 2.45

-0.36 ± 1.84

3.15 ± 2.72

-0.51 ± 2.13

2.76 ± 2.14

-0.21 ± 1.49

  1. 1Data are means ± SD, shown only for those participants who completed the 12 month trial.
  2. §There was no effect of diet group for any variable (repeated measures ANOVA), and no significant difference between baseline measures and those at 12 months for any variable for any diet group (All, No Choice or Choice) except for change in overall SBP (p < 0.001), DBP (p = 0.02) and fasting glucose (p = 0.02) (repeated measures ANOVA).
  3. DBP: diastolic blood pressure, HbA1c: glycosylated haemoglobin, HDL: high-density lipoprotein, hs-CRP: high-sensitivity c-reactive protein, LDL: low-density lipoprotein, SBP: systolic blood pressure.